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Compare Your
Treatment Options
When someone is struggling with depression, OCD, or related conditions, choosing a next step can feel overwhelming. At Bluegrass Advanced Mental Health, we offer an integrated toolkit - from psychotherapy and medication to evidence-based interventional options such as TMS and Spravato (esketamine).
Below is a concise comparison to help you understand how each approach works, who it helps, how quickly it acts, and what to expect.
Treatment Comparison
Compare treatment options side by side to help inform your decisions.
| Treatment | Success Rates | Timeline | Insurance Coverage | Common Side Effects | Best For |
|---|---|---|---|---|---|
| Deep TMS BrainsWay H-Coil | Response ~80%. Remission ~65%. |
Improvement in 2–4 weeks. Treatment duration 4–6 weeks (20–36 daily sessions). |
Typically covered. Usually requires prior authorization and documentation of 2+ failed antidepressant trials. FDA-cleared indication increases coverage likelihood. |
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| Accelerated TMS iTBS Protocol | Response ~80%. Remission ~50%. |
Improvement in 1–2 weeks. Treament duration 1–2 weeks (multiple daily sessions). |
Coverage varies / typically self-pay. Prior authorization required; coverage not guaranteed as the protocol is newer. May require out-of-pocket payment or appeal. |
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| Spravato Esketamine nasal spray + 1 oral antidepressant | Response ~69% at 4 weeks. Remission ~52% by week 4 (MADRS ≤ 12). |
Improvement within hours to days. Initial 2× per week for 4 weeks. Maintenance weekly to monthly. |
Typically covered. Requires prior authorisation, documentation of 2+ failed antidepressant trials, and concurrent oral antidepressant use. Must be administered in a certified clinic with 2-hour observation. |
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| Oral Antidepressants SSRIs, SNRIs, others | Response 50–55%+. Remission ~35–45%+. |
Improvement in 4–6 weeks (full effect 8–12 weeks). Ongoing; 6–12 months minimum after remission. |
Standard coverage. Most medications covered with standard copay; prior authorization may be required for newer or brand-name medications. Generic options typically cost less. |
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| Psychotherapy CBT, IPT, others | Response ~45%. Remission 30–40%. |
Improvement in 6–8 weeks with consistent sessions. Treatment duration 12–20 sessions (3–6 months); may continue longer term. |
Standard coverage. Typically covered under mental health benefits; copay or coinsurance applies per session. Some plans have session limits — verify benefits for specifics. |
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Response ~80%. Remission ~65%.
Improvement in 2–4 weeks. Treatment duration 4–6 weeks (20–36 daily sessions).
Typically covered. Usually requires prior authorization and documentation of 2+ failed antidepressant trials. FDA-cleared indication increases coverage likelihood.
- Mild headache at treatment site
- Scalp discomfort during session
- Temporary lightheadedness
- Muscle twitching during stimulation
- Treatment-resistant depression
- OCD unresponsive to medication
- Patients seeking a non-medication approach
Response ~80%. Remission ~50%.
Improvement in 1–2 weeks. Treament duration 1–2 weeks (multiple daily sessions).
Coverage varies / typically self-pay. Prior authorization required; coverage not guaranteed as the protocol is newer. May require out-of-pocket payment or appeal.
- Mild headache
- Scalp discomfort
- Fatigue from intensive schedule
- Temporary muscle twitching
- Rapid symptom relief needed
- Limited time for standard TMS
- Treatment-resistant depression
Response ~69% at 4 weeks. Remission ~52% by week 4 (MADRS ≤ 12).
Improvement within hours to days. Initial 2× per week for 4 weeks. Maintenance weekly to monthly.
Typically covered. Requires prior authorisation, documentation of 2+ failed antidepressant trials, and concurrent oral antidepressant use. Must be administered in a certified clinic with 2-hour observation.
- Dissociation during treatment
- Dizziness or sedation
- Nausea
- Increased blood pressure (temporary)
- Altered perception
- Treatment-resistant depression
- Need for rapid symptom relief
- Acute suicidal ideation
Response 50–55%+. Remission ~35–45%+.
Improvement in 4–6 weeks (full effect 8–12 weeks). Ongoing; 6–12 months minimum after remission.
Standard coverage. Most medications covered with standard copay; prior authorization may be required for newer or brand-name medications. Generic options typically cost less.
- Weight gain or loss
- Sexual side effects
- Nausea (initial weeks)
- Sleep changes
- Emotional blunting
- First-line depression treatment
- Mild to moderate depression
- Anxiety comorbidity
Response ~45%. Remission 30–40%.
Improvement in 6–8 weeks with consistent sessions. Treatment duration 12–20 sessions (3–6 months); may continue longer term.
Standard coverage. Typically covered under mental health benefits; copay or coinsurance applies per session. Some plans have session limits — verify benefits for specifics.
- Emotional discomfort when processing difficult topics
- Temporary increase in distress
- Time commitment required
- Mild to moderate depression
- Learning coping strategies
- Addressing life stressors
- Combination with medication
Insurance coverage and costs vary by plan and individual circumstances. This comparison is for educational purposes only and does not replace personalised medical advice.
